Applications

Discover the versatility of Bi/ond's organ-on-chip platform and its ability to study complex 3D tissues like organoids, tumor tissue, and even (heart) muscle tissue.

With our innovative technology, you can create an optimal closed environment for your tissue cultures where you can nourish, stimulate and monitor them.

Imagine having the power to grow and maintain organoids, tumor tissue, or muscle tissue in a single well, while also having the ability to recreate a blood vessel-like environment in the underlying channel, which is ideal for administering drugs in a natural way. That's exactly what you get with our Bi/ond organ-on-chip platform!

Our open well allows you to culture your tissue of choice, while the underlying channel can be lined with endothelial cells, imitating the function of a blood vessel. Want to learn more about how to line the channel with endothelial cells? Download our blood vessel brochure here. With our innovative technology, you can create an optimal closed environment for your tissue cultures where you can nourish, stimulate and monitor them.

Some examples of applications:

Organoids

  • Easy microfluidic culture of different organoid tissues in 3D
  • Long-term live observation possible through easy imaging
  • Perform tests in parallel or in series of different organoids
  • Easy recovery of organoids for post-culture assays
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Tumor tissue

  • Easy culture of tumor cells and biopsies with vascularization
  • Study cancer cell vs immune cell interactions  
  • Evaluate the uptake and effect of drugs in tumor tissue
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(Heart) Muscle

  • Easy culture of different muscle tissues with perfusable blood vessels
  • Stimulate growth and maturation of (heart)muscle tissue by mechanic and electric stimulation
  • Study (heart)muscle force and contraction
  • Evaluate the uptake and effect of drugs in (heart) muscle tissue
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Proof of concept studies

These studies can be set up to test if our organ-on-chip platform is capable of stimulating, nourishing and monitoring for instance new cell populations that have not been cultured yet on a chip. Also tests can be set up to see if a certain drug or substance does not interfere with the platform and is suitable for future (drug) research studies. In collaboration with pharmaceutical companies and other research institutes, we have already run a number of proof of principal studies with our platform. Contact us to further explore these opportunities through our contact form!

These studies can be set up to test if our organ-on-chip platform is capable of stimulating, nourishing and monitoring for instance new cell populations that have not been cultured yet on a chip. Also tests can be set up to see if a certain drug or substance does not interfere with the platform and is suitable for future (drug) research studies.

In collaboration with pharmaceutical companies and other research institutes, we have already run a number of proof of principal studies with our platform. Contact us to further explore these opportunities through our contact form!

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